No one seems to appreciate getting old. No doubt because of where it leads! Woody Allen quipped, “I don’t want to achieve immortality through my work. I want to achieve it through not dying.”
Aging celebrities fight this process with face-freezing injections and plastic surgery. But wise men and women understand that while you can’t stop the clock, you can slow it down. These people look beyond the symptoms to take action against the cause of aging.
Here’s how two PhD researchers define aging:
“Aging in mammals is...a decline in physiological functions resulting from cumulative damage to tissues that overwhelms the body’s natural ability to repair them.”1
And what causes the majority of this damage? UC Berkeley professor of biochemistry and molecular biology, Bruce N. Ames, stated that “The degenerative diseases of aging...are increasingly found to have, in good part, an oxidative origin.”2
We can’t live without oxygen but we need to realize oxygen reactions generate oxidants or free radicals. Dr. Ames also stated that each cell of the body is hit by free radicals 10,000 times every day.3
Unlike other injuries, you cannot feel what is happening with free radical damage. Perhaps we need to consider this shocking comparison from a study published in The Proceedings of the National Academy of Science:
“Oxidant by-products of normal metabolism cause extensive damage to DNA, protein, and lipid. We argue that this damage (the same as that produced by radiation) is a major contributor to aging and to degenerative diseases of aging...”4 Oxidative damage is as harmful as radiation damage!
The following radicals are responsible for oxidative damage done in the body:
Superoxide, alkoxyl peroxide, hydroxyl, nitric oxide, hydroperoxyl, singlet oxygen, hypochlorous acid (bleach!), hydrogen peroxide
Free radicals are atoms or molecules that have an unpaired electron desperately seeking to become a pair. When the unpaired electron steals an electron to be balanced again, a new free radical is formed creating a chain reaction that can cause biological damage.
Free radical attacks can be directed at the outside of a cell. Cell membranes are made of unsaturated lipids (fats). Lipid molecules are very susceptible to free radical or oxidative damage. If the cell wall is damaged badly, it becomes hardened (lipid peroxidation) and the cell cannot get nutrients in or waste material out. And the cell won’t be able to get signals from other cells so it can perform its function.
Free radical attacks also occur within a cell and perhaps are more insidious. Every cell contains double-strand DNA which provides chemical instructions for what the cell is to do. This cellular DNA resides in the nucleus of cells.
The “energy factories” of each cell are called mitochondria where the energy to fuel the cell is created. The mitochondria have a single strand DNA, called “mitochondria DNA” or mtDNA. In Dr. Keller’s glutathione monograph he writes, “...cellular DNA has developed multiple defenses against free radical damage but these protections are absent or have not yet developed in mtDNA.”5 What protects the delicate spiral of mtDNA? The powerful antioxidant glutathione is one protector.
The hydroxyl radical causes no end of cellular and DNA damage but even worse, it “cascades.” If this free radical is not “quenched” or stopped by an antioxidant, a carbon-centered radical that reacts with oxygen to create the peroxyl radical which then can react with other fatty acids or proteins. One researcher has described how peroxynitrite, another cascading free radical, attacks an enzyme crucial to the energy cycle, causing a drop in ATP (the energy that fuels your cells).6 You WILL feel this loss of energy.
Dr. Keller explains that during the energy creation process in the mitochondria, the superoxide free radical is produced. The antioxidant enzyme called superoxide dismutase (SOD) coverts it to a hydroxyl group and hydrogen peroxide, both of which are free radicals themselves. That is the first step to neutralizing this radical. But superoxide dismutase now needs more antioxidant help to finish the job.
Antioxidants: Heroes to the Rescue!
Thankfully, our bodies provide many powerful antioxidants to halt or slow the damage done by free radicals. You’ve heard of the antioxidants we can take into our bodies like vitamin A, E and C
There are four powerful antioxidants actually created inside the body:
• Glutathione (GSH)
• Superoxide dismutase (SOD)
• Catalase (CAT)
• Coenzyme Q10 (CoQ10)
Superoxide dismutase starts breaking down the highly damaging superoxide free radical but needs glutathione and catalase to finish the job by neutralizing the hydroxyl and hydrogen peroxide radicals.
Glutathione has often been called the most important intracellular defense against free radical damage. But Dr. Keller says its most important claim to fame is that glutathione “alone in the antioxidant world, regenerates (recycles) directly and indirectly, a variety of other antioxidants including vitamin C, CoQ10, vitamin E and vitamin A.”7 Catalase converts hydrogen peroxide into water and oxygen. Coenzyme Q10 or CoQ10 provides hydrogen atoms to reduce (quench) the peroxyl and the alkoxyl radical.
The Immense Value of MaxGXL and Max N-Fuze
What does your body need in order to have not just free radical protection but SUPER free radical protection? You need the building blocks of glutathione. You need the other three endogenous (created in the body) antioxidants: superoxide dismutase, catalase and CoQ10.
You need the vitamins and minerals that are co-factors in the utilization of these antioxidants. Here is a “for instance.” Substances that assist in the production of glutathione and the five antioxidant glutathione enzymes are called co-factors. Important glutathione co-factors include the trace mineral selenium, vitamins B1 and B2, vitamin C, B6, B12, folic acid, vitamin E and other micronutrients.
Can you see how MaxGXL and Max N-Fuze work synergistically to provide nutrients and needed antioxidants for your increased health?
Arm your body with a full arsenal of antioxidants by providing the building blocks and co-factors needed for this amazing production. Your body knows what to do with these ingredients.
Maximize your health with MaxGXL and Max N-Fuze!
Notes
1. Muhammed Majeed, PhD and Lakshmi Prakash PhD, “Aging, Biomorphosis Life Span and Phytonutrients,” Sabinsa Corporation White Paper, 2007.
2. Bruce N. Ames, “The Causes and Prevention of Cancer,” http://users.rcn.com/jkimball.ma.ultranet/ BiologyPages/A/Ames_Causes.html. [Emphasis added.]
3. Jane E. Brody, “Scientist at Work: Bruce N. Ames; Strong Views on the Origins of Cancer,” The New York Times, July 5, 1994.
4. Ames BN, Shigenaga MK, Hagen TM, “Oxidants, antioxidants, and the degenerative diseases of aging,” Proc. Natl. Acad. Sci. Vol. 90, September 1993, 7915-7922. [Emphasis added.]
5. Robert H. Keller, Glutathione: Your Best Defense Against Aging, Cellular Damage and Disease, p. 14-15, , 2008, ISBN 978-0-615-26451-6.
6. Pall M, “Elevated, sustained peroxynitrite levels as the cause of chronic fatigue syndrome,” Medical Hypotheses (2000) 54(1):115-125.
7. Keller, ibid, page 26.
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Posted 04:00 PM February 04, 2009
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