CD Bioparticles

Targeted Anti-Tumor Antibody-Drug Conjugates

Antibody-drug conjugates (ADCs) are conjugated products of monoclonal antibodies (mAbs) and cytotoxic small molecules. In tumor treatment, although monoclonal antibodies have good targeting properties, most of them target extracellular or cell surface antigens, have weak anti-tumor activity, have limited therapeutic effect on solid tumors, and are more likely to develop drug resistance; conventional anti-tumor chemotherapy Although drugs have high anti-tumor cell activity, they lack targeting... READ MORE Posted April 04, 2024 at 02:40 AM

Dyed Polystyrene Latex Particles

What are Dyed Polystyrene Latex Particles? Polystyrene particles (PSP) are commercially available in different sizes, ranging from 15 nanometers to several micrometers, with narrow size distributions and various surface chemistries. Additionally, polystyrene is generally considered inert and nontoxic, making it safe for use in a variety of biological assays. Dyed polystyrene latex particles or colored latex beads have excellent multiplexing capability and have the following cha... READ MORE Posted April 04, 2024 at 02:34 AM

Application of Nanoformulation in Transdermal Drug Delivery System

As a promising systemic drug delivery method, transdermal drug delivery system (TDDS) is easier and more convenient to operate than traditional oral, intravenous and subcutaneous injection methods. It can improve patient compliance while also avoiding First-pass effect and drug side effects. As the largest organ of the human body, the skin is also the body’s first line of defense against foreign microorganisms and chemical substances. Its drug permeability is lower, which is orders ... READ MORE Posted March 10, 2024 at 07:10 PM

Zeta Potential: A Fundamental Measure for Colloidal Behavior

What is Zeta Potential? Figure 1. Electrical double layer at the surface of solution-phase nanoparticles. Zeta potential (ZP) is a physical property exhibited by any particle in a suspension, macromolecule or material surface. ZP is an analytical technique used to determine the surface charge of nanoparticles in colloidal solutions. The surface of a charged particle attracts and binds firmly to a thin layer of opposite charge, forming a thin layer of liquid called the Stern layer; as the part... READ MORE Posted March 10, 2024 at 07:08 PM

Application of Carrageenan Hydrogel in Biomedical Field

Hydrogel is a three-dimensional network of hydrophilic polymers that swells in water without dissolving. Because the polymer contains a large number of hydrophilic groups, the hydrogel can absorb and lock a large amount of water. After absorbing water, the hydrogel network can maintain its original shape without being destroyed. Hydrogels are widely used in tissue engineering, drug delivery, biosensing, etc. due to their simple preparation, strong tunability of mechanical properties, good bio... READ MORE Posted February 18, 2024 at 11:07 PM

Unveiling the Mystery of Plasmons

Surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS) are two key surface plasmon technologies that ultimately enable single-molecule-level chemical and biological sensors. Due to the tremendous progress in solution-based synthesis methods, plasmonic nanoparticles with various complex shapes (e.g., spheres, rods, and prisms) have been widely used for surface plasmon resonance and surface-enhanced Raman scattering sensing. Localized surface plasmon resonance (LSPR) aroun... READ MORE Posted February 18, 2024 at 11:06 PM

Micelle vs Liposome

Micelles refer to molecularly ordered aggregates that begin to form in large quantities after the surfactant concentration reaches a certain value in an aqueous solution. In micelles, the hydrophobic groups of surfactant molecules aggregate to form the core of the micelle, and the hydrophilic polar groups form the outer layer of the micelle. Liposomes are an artificial membrane. In the water, the hydrophilic head of the phospholipid molecule is inserted into the water, and the hydrophobic tai... READ MORE Posted January 18, 2024 at 01:49 AM

Gold Nanoparticles in Medicine: A Tiny Marvel with Big Potential

With the continuous development of nanotechnology, gold nanoparticles are widely used in the field of medicine. Gold nanoparticles not only have good controllability, biocompatibility, and biosorption, but also have a high degree of stability, and can achieve specific biometrics and functions through surface modification. Therefore, it has become an important nanomaterial in biomedicine. The Role of Gold Nanoparticles Gold nanoparticles alias AuNPs and nano gold, their diameters are 1~10... READ MORE Posted January 18, 2024 at 01:41 AM

Application of 3D Printing

Introduction to 3D Printing In the 1980s, American engineer Charles Hull developed rapid prototyping technology by combining points and surfaces and then using light reinforcement. After numerous failures, he finally invented stereolithography technology. Based on this technology, the world’s The first 3D printer came into being. By the end of the 1990s, researchers combined 3D printing technology with the field of medical care to create substitutes for human organs for adjuvant treatment, wh... READ MORE Posted December 18, 2023 at 12:25 AM

Mastering Colloidal Gold Handling, Storage, and Applications

Colloidal gold is a certain-size gold particle synthesized by gold ion reduction and polymerization of chloroauric acid (HAuCl4) under the action of reducing agents such as white phosphorus, ascorbic acid, sodium citrate, tannic acid, and so on. Due to electrostatic action, gold particles repel each other and suspend into a stable colloidal state, forming a negatively charged hydrophobic colloid solution, so it is called colloidal gold. Colloidal gold has high electron density and can co... READ MORE Posted December 18, 2023 at 12:23 AM