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Updates from Businesses in Shirley, NY 11967
An Insight into Proteolysis Targeting Chimeras (PROTACs)
Proteolysis Targeting Chimeras (PROTACs) are emerging as a promising therapeutic tool in the world of molecular and medical biology. As the daunting complexity of diseases unfolds, the need for more precise and targeted tactics to mitigate pathological conditions is intensifying. PROTACs have novel pharmaceutical potential, enabli... Read More
An Overview of Functional Peptides
If we were to delve into the intricate world of biochemistry, we would come across the functionality of diverse molecules that perform essential roles in biological systems. One such class of molecules, peptides, are short chains of amino acid monomers linked by peptide bonds. These aren't just any ordinary molecules; these are functio... Read More
Antibiotic Potency Test
What is Antibiotic Potency Test? A microbiological potency assay measures the bioactivity or potency of an antibiotic by the degree of growth repression on susceptible microorganisms at different concentrations. All antibiotic products must go through potency testing prior to market release. Both the EP and the USP require testing of a... Read More
PLGA Nano Drug Carrier
Poly(lactic-co-glycolic acid) (PLGA) is a functional polymer organic compound randomly polymerized by lactic acid (PLA) and glycolic acid (PGA). It has been approved by the U.S. Food and Drug Administration It is certified by the Food and Drug Administration (FDA) and is a copolymer material available on the market. PLGA has good bioco... Read More
Colored Polystyrene Particles in Point-of-Care Diagnostics
What is POCT? Multiplexed point-of-care testing POCT (Point-of-Care Testing) refers to clinical and bedside testing conducted in close proximity to patients. It is often not performed by clinical laboratory personnel. POCT holds significant importance in disease prevention, etiology determination, prognosis, enhancing treatment outcome... Read More
Overview of ADC Combination Therapies
Antibody-drug conjugates (ADCs) have emerged as a promising class of treatments in the evolving field of cancer treatment. ADCs combine the potency of cytotoxic drugs with the selectivity of monoclonal antibodies, providing a novel approach to targeted therapy. ADCs show great promise in the fight against cancer and have the poten... Read More
What is Nanogel and Its Classifications?
Nanogels (NGs), namely nanoscale hydrogel particles, are three-dimensional network systems formed by physical orchemical cross-linking of polymers. Nanogels have received widespread attention in recent years due to their unique properties and potential applications in various fields such as drug delivery, tissue engineering, and d... Read More
What are Radionuclide Drug Conjugates (RDCs)?
Coupling drugs combine the precise targeting and potent killing properties, has become a widely recognized form of medication in recent years. Radioactive drug conjugates (RDCs), as a particular form of coupling drugs, are formed by combining radioactive isotopes with disease-targeting molecules. According to the application of RDCs, t... Read More
Challenges in Small Molecule Targeted Drug Development
The classical mode of action of small molecule drugs is "occupancy-driven". Since the FDA approved the first oral small molecule targeted therapy for tumors-tamoxifen targeting the estrogen receptor (ER)-in 1977 for the treatment of breast cancer, small molecule drug development has typically focused on screening for high-affinity inhi... Read More
BOC Sciences to Present at the 2024 TIDES USA Conference
BOC Sciences, a globally renowned supplier with over a decade of experience in the biochemical supply chain, is thrilled to announce its participation in this year's TIDES USA or the Oligonucleotide and Peptide Therapeutics conference. The BOC Sciences team will showcase its cutting-edge products and services at booth #9... Read More
Breathing Gas Pathways in Medical Devices
Biocompatibility evaluation of breathing gas pathways in medical devices is a powerful tool for the evaluation of contaminants from the air emitted from the device for Volatile Organic Compounds (VOCs) and particulate matter when the gas pathway is intended to contact a patients’ respiratory tract. Standard for Biocompatibility Ev... Read More
Targeted Anti-Tumor Antibody-Drug Conjugates
Antibody-drug conjugates (ADCs) are conjugated products of monoclonal antibodies (mAbs) and cytotoxic small molecules. In tumor treatment, although monoclonal antibodies have good targeting properties, most of them target extracellular or cell surface antigens, have weak anti-tumor activity, have limited therapeutic effect on solid tum... Read More
Dyed Polystyrene Latex Particles
What are Dyed Polystyrene Latex Particles? Polystyrene particles (PSP) are commercially available in different sizes, ranging from 15 nanometers to several micrometers, with narrow size distributions and various surface chemistries. Additionally, polystyrene is generally considered inert and nontoxic, making it safe for use in a v... Read More
Preparation Methods of Microspheres
There are various techniques for the preparation of microspheres, and the selection of an appropriate method depends on the physicochemical properties of the drug. Currently, the most widely used methods includeemulsion evaporation, phase separation, spray drying, and hot-melt extrusion, each with corresponding products on the market. ... Read More
BOC Sciences to Exhibit at Drug Discovery Chemistry 2024, Booth #117
BOC Sciences, a tech-driven company, is delighted to announce that its team will be participating in the prestigious Drug Discovery Chemistry (DDC) conference in April 2024. The company will be situated at booth #117, showcasing its quality chemical materials and advanced technologies. DDC is an annual event th... Read More