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Updates from Businesses in Shirley, NY

An Insight into Proteolysis Targeting Chimeras (PROTACs)

Proteolysis Targeting Chimeras (PROTACs) are emerging as a promising therapeutic tool in the world of molecular and medical biology. As the daunting complexity of diseases unfolds, the need for more precise and targeted tactics to mitigate pathological conditions is intensifying. PROTACs have novel pharmaceutical potential, enabli... Read More

May 30, 2024

An Overview of Functional Peptides

If we were to delve into the intricate world of biochemistry, we would come across the functionality of diverse molecules that perform essential roles in biological systems. One such class of molecules, peptides, are short chains of amino acid monomers linked by peptide bonds. These aren't just any ordinary molecules; these are functio... Read More

May 29, 2024

Antibiotic Potency Test

What is Antibiotic Potency Test? A microbiological potency assay measures the bioactivity or potency of an antibiotic by the degree of growth repression on susceptible microorganisms at different concentrations. All antibiotic products must go through potency testing prior to market release. Both the EP and the USP require testing of a... Read More

May 10, 2024

PLGA Nano Drug Carrier

Poly(lactic-co-glycolic acid) (PLGA) is a functional polymer organic compound randomly polymerized by lactic acid (PLA) and glycolic acid (PGA). It has been approved by the U.S. Food and Drug Administration It is certified by the Food and Drug Administration (FDA) and is a copolymer material available on the market. PLGA has good bioco... Read More

May 09, 2024

Colored Polystyrene Particles in Point-of-Care Diagnostics

What is POCT? Multiplexed point-of-care testing POCT (Point-of-Care Testing) refers to clinical and bedside testing conducted in close proximity to patients. It is often not performed by clinical laboratory personnel. POCT holds significant importance in disease prevention, etiology determination, prognosis, enhancing treatment outcome... Read More

May 09, 2024

Overview of ADC Combination Therapies

Antibody-drug conjugates (ADCs) have emerged as a promising class of treatments in the evolving field of cancer treatment. ADCs combine the potency of cytotoxic drugs with the selectivity of monoclonal antibodies, providing a novel approach to targeted therapy. ADCs show great promise in the fight against cancer and have the poten... Read More

Apr 26, 2024

What is Nanogel and Its Classifications?

Nanogels (NGs), namely nanoscale hydrogel particles, are three-dimensional network systems formed by physical orchemical cross-linking of polymers. Nanogels have received widespread attention in recent years due to their unique properties and potential applications in various fields such as drug delivery, tissue engineering, and d... Read More

Apr 26, 2024

What are Radionuclide Drug Conjugates (RDCs)?

Coupling drugs combine the precise targeting and potent killing properties, has become a widely recognized form of medication in recent years. Radioactive drug conjugates (RDCs), as a particular form of coupling drugs, are formed by combining radioactive isotopes with disease-targeting molecules. According to the application of RDCs, t... Read More

Apr 26, 2024

Challenges in Small Molecule Targeted Drug Development

The classical mode of action of small molecule drugs is "occupancy-driven". Since the FDA approved the first oral small molecule targeted therapy for tumors-tamoxifen targeting the estrogen receptor (ER)-in 1977 for the treatment of breast cancer, small molecule drug development has typically focused on screening for high-affinity inhi... Read More

Apr 26, 2024

BOC Sciences to Present at the 2024 TIDES USA Conference

BOC Sciences, a globally renowned supplier with over a decade of experience in the biochemical supply chain, is thrilled to announce its participation in this year's TIDES USA or the Oligonucleotide and Peptide Therapeutics conference. The BOC Sciences team will showcase its cutting-edge products and services at booth #9... Read More

Apr 26, 2024

Breathing Gas Pathways in Medical Devices

Biocompatibility evaluation of breathing gas pathways in medical devices is a powerful tool for the evaluation of contaminants from the air emitted from the device for Volatile Organic Compounds (VOCs) and particulate matter when the gas pathway is intended to contact a patients’ respiratory tract. Standard for Biocompatibility Ev... Read More

Apr 07, 2024

Targeted Anti-Tumor Antibody-Drug Conjugates

Antibody-drug conjugates (ADCs) are conjugated products of monoclonal antibodies (mAbs) and cytotoxic small molecules. In tumor treatment, although monoclonal antibodies have good targeting properties, most of them target extracellular or cell surface antigens, have weak anti-tumor activity, have limited therapeutic effect on solid tum... Read More

Apr 04, 2024

Dyed Polystyrene Latex Particles

What are Dyed Polystyrene Latex Particles? Polystyrene particles (PSP) are commercially available in different sizes, ranging from 15 nanometers to several micrometers, with narrow size distributions and various surface chemistries. Additionally, polystyrene is generally considered inert and nontoxic, making it safe for use in a v... Read More

Apr 04, 2024

Preparation Methods of Microspheres

There are various techniques for the preparation of microspheres, and the selection of an appropriate method depends on the physicochemical properties of the drug. Currently, the most widely used methods includeemulsion evaporation, phase separation, spray drying, and hot-melt extrusion, each with corresponding products on the market. ... Read More

Mar 27, 2024

BOC Sciences to Exhibit at Drug Discovery Chemistry 2024, Booth #117

BOC Sciences, a tech-driven company, is delighted to announce that its team will be participating in the prestigious Drug Discovery Chemistry (DDC) conference in April 2024. The company will be situated at booth #117, showcasing its quality chemical materials and advanced technologies. DDC is an annual event th... Read More

Mar 27, 2024