Mesena is located in Warren County. The county is rural area located in east-central Georgia. Major attractions that can be found within 20 minutes from the town include, 20 public and private golf courses and arts and entertainment from the ballet, the symphony, and many museums. Major attractions include The old Knox Theater and The Ogeechee River Mill. The biggest schools in the area include Warren County High School and Warren County Middle School. Local businesses in the area include Empire Services and Thomson Senior Property.